Neoadjuvant Treatment in Stage IIIA (N2) Non Small Cell Lung Cancer: Evaluating Surgical Outcomes and Prognostic Impact of Induction Chemotherapy

Authors

  • Asmaa Magdy Mahmoud Hafez, Maher Abdelhameed Aidarous, Karim Mohamed Elfakharany, Heba Mounir Abdelhameed , Ahmed Zain- Elabdeen Al Attar

Keywords:

Neoadjuvants, Non-Small Cell Lung Cancer, Chemotherapy

Abstract

Background: Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality worldwide, with stage IIIA (N2) disease presenting a particularly complex therapeutic challenge. Historically, the management of potentially resectable stage IIIA (N2) NSCLC has evolved from surgery alone to a multidisciplinary approach involving neoadjuvant and induction therapies. Induction chemotherapy and induction chemoradiation represent the primary neoadjuvant modalities, each with distinct biological rationales and clinical implications.

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References

Goldstraw P, Chansky K, Crowley J, et al. The IASLC lung cancer staging project: proposals for revision of the TNM stage groupings in the forthcoming (8th) edition of the TNM classification for lung cancer. J Thorac Oncol. 2016;11(1):39-51.

Detterbeck FC, Boffa DJ, Kim AW, Tanoue LT. The eighth edition lung cancer stage classification. Chest. 2017;151(1):193-203.

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Published

2024-06-30

How to Cite

Asmaa Magdy Mahmoud Hafez, Maher Abdelhameed Aidarous, Karim Mohamed Elfakharany, Heba Mounir Abdelhameed , Ahmed Zain- Elabdeen Al Attar. (2024). Neoadjuvant Treatment in Stage IIIA (N2) Non Small Cell Lung Cancer: Evaluating Surgical Outcomes and Prognostic Impact of Induction Chemotherapy . Pegem Journal of Education and Instruction, 14(3), 598–603. Retrieved from https://pegegog.net/index.php/pegegog/article/view/4222

Issue

Vol. 14 No. 3 (2024): PEGEGOG

Section

Article

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