Evaluation of Serum Factor H and Anti-Factor H Antibodies in Childhood Hemolytic Uremic Syndrome: A Comprehensive Review

Authors

  • Hany Elsayed Ibrahim, Mohamed Reda Abdelkader, Amal Saeed El Shal and Mohamed Ragab Abdellatif

Keywords:

Factor H, Childhood, Hemolytic Uremic Syndrome

Abstract

Hemolytic uremic syndrome (HUS) is a leading cause of acute kidney injury (AKI) in children, characterizedby the triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal impairment. While typical HUS is oftenlinked to Shiga toxin–producing Escherichia coli (STEC), atypical HUS (aHUS) results from dysregulation of thealternative complement pathway.

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References

Noris M, Remuzzi G. Hemolytic uremic syndrome. J Am Soc Nephrol. 2005;16(4):1035-1050.

Tarr PI, Gordon CA, Chandler WL. Shiga-toxin–producing Escherichia coli and haemolytic uraemic syndrome. Lancet. 2005;365(9464):1073-1086.

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Published

2024-03-20

How to Cite

Hany Elsayed Ibrahim, Mohamed Reda Abdelkader, Amal Saeed El Shal and Mohamed Ragab Abdellatif. (2024). Evaluation of Serum Factor H and Anti-Factor H Antibodies in Childhood Hemolytic Uremic Syndrome: A Comprehensive Review . Pegem Journal of Education and Instruction, 14(3), 699–708. Retrieved from https://pegegog.net/index.php/pegegog/article/view/4249

Issue

Vol. 14 No. 3 (2024): PEGEGOG

Section

Article

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