Regulatory T Cells (Tregs) in systemic lupus erythematosus

Authors

  • Yasser Abd Elmonem El -Hendy, Ghada Elsaid Amr, Osama Ragab Youssif, Ahmed Noaman Elsayed, Mohamed Elmarzouky Kewan

Keywords:

Regulatory T Cells, systemic lupus erythematosus

Abstract

Background: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the loss of immunetolerance and the production of autoantibodies targeting various nuclear antigens. Regulatory T cells (Tregs), crucial formaintaining immune homeostasis, exhibit significant dysregulation in SLE, contributing to its pathogenesis, clinical presentation, prognosis, and response to treatment

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References

La Cava A. T-regulatory cells in systemic lupus erythematosus. Lupus. 2008;17:421–5.

Shevach EM. Mechanisms of Foxp3+ T regulatory cell-mediated suppression. Immunity. 2009;30:636–45.

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Published

2024-03-20

How to Cite

Yasser Abd Elmonem El -Hendy, Ghada Elsaid Amr, Osama Ragab Youssif, Ahmed Noaman Elsayed, Mohamed Elmarzouky Kewan. (2024). Regulatory T Cells (Tregs) in systemic lupus erythematosus. Pegem Journal of Education and Instruction, 14(3), 792–804. Retrieved from https://pegegog.net/index.php/pegegog/article/view/4374

Issue

Vol. 14 No. 3 (2024): PEGEGOG

Section

Article

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