Brain MRI and MR Spectroscopy in Pediatric Mucopolysaccharidoses: Diagnostic Utility, Biomarkers, and Correlation with Neurodevelopment

Authors

  • Seham Fathy Abd Elhamid Azab, Mohamed Refaat Beshir, Wesam Abd Elmonem Mokhtar, Tamer Abdelhak Hassan, Mohamed Tamer Ibrahem

Keywords:

Brain MRI and MR Spectroscopy, Mucopolysaccharidoses

Abstract

Background: Pediatric mucopolysaccharidoses (MPS) encompass a group of lysosomal storage disorders characterizedby deficient degradation of glycosaminoglycans, leading to progressive multisystem and central nervous system (CNS)involvement. Brain magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) have emerged ascritical tools for identifying and quantifying

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References

Shapiro EG, King K, Ahmad A. Neurobehavioral aspects of mucopolysaccharidoses. J Inherit Metab Dis. 2017;40(4):499512.

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Published

2024-03-20

How to Cite

Seham Fathy Abd Elhamid Azab, Mohamed Refaat Beshir, Wesam Abd Elmonem Mokhtar, Tamer Abdelhak Hassan, Mohamed Tamer Ibrahem. (2024). Brain MRI and MR Spectroscopy in Pediatric Mucopolysaccharidoses: Diagnostic Utility, Biomarkers, and Correlation with Neurodevelopment . Pegem Journal of Education and Instruction, 14(3), 835–842. Retrieved from https://pegegog.net/index.php/pegegog/article/view/4464

Issue

Vol. 14 No. 3 (2024): PEGEGOG

Section

Article

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