Adjuvant Hypofractionated Radiotherapy for Early Breast Cancer
Keywords:
Adjuvant , Hypofractionated Radiotherapy, Breast CancerAbstract
Background: Adjuvant radiotherapy following breast-conserving surgery or mastectctomy is a fundamental component
of curative treatment for early breast cancer. Historically, radiotherapy was delivered using conventional fractionation
over five to six weeks. However, increasing understanding of breast cancer radiobiology, coupled with the need to improve
patient convenience and healthcare efficiency, led to the development of moderately hypofractionated radiotherapy
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Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet. 2011;378(9804):1707-1716. doi:10.1016/S0140-6736(11)61629-2
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