Advanced Cardiac MRI Techniques Beyond Late Gadolinium Enhancement in Ischemic Heart Disease: Current Evidence and Future Directions
Keywords:
Cardiac MRI Techniques, Late Gadolinium Enhancement , Ischemic Heart DiseaseAbstract
Background: Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) has long been regarded asthe reference standard for noninvasive detection and quantification of myocardial infarction in ischemic heart disease.While LGE provides robust visualization of focal replacement fibrosis, it has important limitations, including reducedsensitivity for diffuse interstitial fibrosis, dependence on gadolinium-based contrast agents, and limited ability to characterize dynamic or subtle myocardial injury.
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Rajiah P, François CJ, Leiner T. Cardiac MRI: state of the art. Radiology. 2023;307(3):e223008.
Busse A, Rajagopal R, Yücel S, et al. Cardiac MRI—update 2020. Radiologe. 2020;60:33–46.
Kim RJ, Wu E, Rafael A, et al. The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med. 2000;343(20):1445–1453.
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