Circulating and Tissue lncRNAs CASC2 and TUG1 as Prognostic Biomarkers in HCV-Associated Hepatocellular Carcinoma
Keywords:
lncRNAs, CASC2, TUG1 , HCV-Associated Hepatocellular CarcinomaAbstract
Background: Hepatocellular carcinoma (HCC) arising in the setting of chronic hepatitis C virus (HCV) infection ischaracterized by marked biological heterogeneity and highly variable clinical outcomes. Despite advances in antiviraltherapy and improvements in locoregional and systemic treatments, prognosis remains poor for many patients due to high rates of tumor recurrence, vascular invasion,
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Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-424.
El-Serag HB. Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology. 2012;142(6):1264-1273.
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