Comprehensive Evaluation of Musculoskeletal Status in Children with Hemophilia: Clinical, Radiologic, and Functional Perspective
Keywords:
Pediatric hemophilia, hemophilic arthropathy, joint health assessmentAbstract
Background: Hemophilia is a hereditary bleeding disorder characterized by recurrent musculoskeletal hemorrhages that
begin early in life and frequently lead to progressive joint damage and long-term disability. Despite advances in
prophylactic therapy, hemophilic arthropathy remains a significant clinical concern, particularly in pediatric populations
where early joint changes may be subtle or subclinical. Accurate and timely evaluation of musculoskeletal status is
therefore essential to detect early joint involvement, monitor disease progression, and guide individualized management
strategies aimed at preserving joint function and quality of life.
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References
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Gualtierotti R, Solimeno LP, Peyvandi F. Hemophilic arthropathy: current knowledge and future perspectives. J Thromb
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