Comprehensive Evaluation of Musculoskeletal Status in Children with Hemophilia: Clinical, Radiologic, and Functional Perspective

Authors

  • Mervat ATfy Mohammed , Hossam Mostafa Kamal , Mohamed Atia Mortada , Moursy Mabrouk Abdallah Attia Moursy

Keywords:

Pediatric hemophilia, hemophilic arthropathy, joint health assessment

Abstract

Background: Hemophilia is a hereditary bleeding disorder characterized by recurrent musculoskeletal hemorrhages that
begin early in life and frequently lead to progressive joint damage and long-term disability. Despite advances in
prophylactic therapy, hemophilic arthropathy remains a significant clinical concern, particularly in pediatric populations
where early joint changes may be subtle or subclinical. Accurate and timely evaluation of musculoskeletal status is
therefore essential to detect early joint involvement, monitor disease progression, and guide individualized management
strategies aimed at preserving joint function and quality of life.

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References

Srivastava A, Santagostino E, Dougall A, Kitchen S, Sutherland M, Pipe SW, et al. WFH guidelines for the management

of hemophilia, 3rd edition. Haemophilia. 2020;26(Suppl 6):1-158.

Peyvandi F, Garagiola I, Young G. The past and future of haemophilia: diagnosis, treatments, and complications. Lancet.

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Gualtierotti R, Solimeno LP, Peyvandi F. Hemophilic arthropathy: current knowledge and future perspectives. J Thromb

Haemost. 2021;19(9):2112-2121.

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Published

2024-04-27

How to Cite

Mervat ATfy Mohammed , Hossam Mostafa Kamal , Mohamed Atia Mortada , Moursy Mabrouk Abdallah Attia Moursy. (2024). Comprehensive Evaluation of Musculoskeletal Status in Children with Hemophilia: Clinical, Radiologic, and Functional Perspective . Pegem Journal of Education and Instruction, 14(3), 1032–1041. Retrieved from https://pegegog.net/index.php/pegegog/article/view/5014

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